Arterial hypertension in a very old: Significance of the biological age

Elderly population is heterogenic, and persons with the same chronological age differ greatly by their physical and cognitive functioning. Regardless the convincing witness on the adverse influence of raised blood pressure (BP) in a middle age persons, its influence on the prognosis of a very old is still debatable, as the question, whether to treat arterial hypertension (AH) in elderly, and if so, how intensively. The article focuses on the results of observational and randomized clinical studies that make it to decide that not the chronological, but biological age is an important criteria for decision on AH management in elderly. The article presents in details mechanisms interacting in BP regulation, and influence of BP on the risk of morbidity and mortality in elderly. Also, the current guidelines are cited, on antihypertension treatment, as the issues dicussed on AH treatment in elderly, that require further investigation.

Authors
Kotovskaya Y.V. 1, 2 , Tkacheva O.N.1 , Rukikhina N.K.1 , Ostapenko V.S.1
Publisher
Vserossiiskoe Obshchestvo Kardiologov
Number of issue
3
Language
Russian
Pages
87-96
Status
Published
Volume
16
Year
2017
Organizations
  • 1 N. I. Pirogov Russian National Research Medical University (RNRMU), SD Russian Gerontological Scientific-Clinical Center, Moscow, Russian Federation
  • 2 Peoples'Friendship University of Russia, Moscow, Russian Federation
Keywords
A Very Old; Arterial Hypertension; Biological Age.; Frailty; Orthostatic Hypotension
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/5938/
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