Entrepreneurship and Sustainability Issues.
Entrepreneurship and Sustainability Center.
Vol. 7.
2019.
P. 814-824
Synthesis of Functionalized Bicyclic Compounds Based on 2-(1-Arylethylidene)malononitriles
New tetrahydroisoquinoline-5,7-dicarbonitrile derivatives have been synthesized by piperazine hydrate-catalyzed reaction of acetoacetanilide with 2-(1-arylethylidene)malononitriles (Knoevenagel condensation products of acetophenones and malononitrile) in aqueous ethanol at room temperature. The product structure was confirmed by NMR spectra and X-ray analysis of 1,6-diamino-4a-methyl-3-oxo-2,8-diphenyl-2,3,4,4a-tetrahydroisoquinoline-5,7-dicarbonitrile. © 2019, Pleiades Publishing, Ltd.
Authors
Naghiyev F.N.1
,
Mamedov I.G.1
,
Asadov K.A.1
,
Dorovatovskii P.V.
2
,
Khrustalev V.N.
3,
4
,
Maharramov A.M.
1
Number of issue
12
Language
English
Pages
1967-1970
Status
Published
Link
Volume
55
Year
2019
Organizations
- 1 Baku State University, Baku, 1148, Azerbaijan
- 2 Kurchatov Institute National Research Center, Moscow, 123182, Russian Federation
- 3 People’s Friendship University of Russia, Moscow, 117198, Russian Federation
- 4 Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, 119991, Russian Federation
Keywords
2-(1-arylethylidene)malononitriles; acetoacetanilide; NMR; tetrahydroisoquinoline-5,7-dicarbonitriles; X-ray analysis
Date of creation
10.02.2020
Date of change
10.02.2020
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Other records
Russian Journal of Coordination Chemistry/Koordinatsionnaya Khimiya.
Vol. 45.
2019.
P. 867-875