β-Amyloid: Alzheimer's Disease and Brain β-Amyloidoses

This review considers some aspects of the biochemistry of β-amyloid, a protein which produces insoluble deposits in the brain. These deposits are a specific morphological feature of Alzheimer's disease, Down's syndrome, and senile dementia. Our contribution to the concept of a soluble form of β-amyloid as of a normal human protein is presented.

Authors
Koudinova N.V.1 , Berezov T.T. 1, 2 , Koudinov A.R.1, 3
Number of issue
7
Language
English
Pages
752-757
Status
Published
Volume
64
Year
1999
Organizations
  • 1 Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, ul. Pogodinskaya 10, Moscow 119832, Russian Federation
  • 2 Department of Biochemistry, School of Medicine, Russ. People's Friendship University, ul. Miklukho-Maklaya 8, Moscow 117198, Russian Federation
  • 3 Natl. Mental Health Research Center, Russian Academy of Medical Sciences, Zagorodnoe Shosse 2/2, Moscow 113152, Russian Federation
Keywords
β-amyloid; β-amyloid precursor; Alzheimer's disease; Lipid metabolism
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/549/
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