Solvent-free Buchwald–Hartwig amination with low palladium loadings

A highly efficient ‘green’ solvent-free monoarylation of primary anilines with aryl bromides mediated by the expanded-ring N-heterocyclic carbene palladium complex (THP-Dipp)Pd(cinn)Cl [THP-Dipp is 1,3-bis(2,6-diisopropylphenyl)-3,4,5,6-tetrahydropyrimidin-2-ylidene; cinn is cinnamyl] can be performed at low catalyst loadings (0.1 mol%) to provide excellent yields and remarkable selectivities for various substrates. © 2017

Authors
Chesnokov G.A.1 , Gribanov P.S.2 , Topchiy M.A.2 , Minaeva L.I. 3 , Asachenko A.F. 2, 3 , Nechaev M.S.1, 2 , Bermesheva E.V.2, 4 , Bermeshev M.V.2
Journal
Mendeleev Communications
Publisher
Royal Society of Chemistry
Number of issue
6
Language
English
Pages
618-620
Status
Published
Link
External link
DOI
10.1016/j.mencom.2017.11.027
Volume
27
Year
2017
Organizations
  • 1 Department of Chemistry, M. V. Lomonosov Moscow State University, Moscow, 119991, Russian Federation
  • 2 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, Moscow, 119991, Russian Federation
  • 3 Peoples Friendship University of Russia (RUDN University), Moscow, 117198, Russian Federation
  • 4 I. M. Sechenov First Moscow State Medical University, Moscow, 119991, Russian Federation
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/5236/
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