Domino Reactions of 1-Aroyl-3,4-dihydroisoquinolines with α,β-Unsaturated Aldehydes

An efficient synthesis of pyrrolo[2,1- a ]isoquinolines by a domino reaction from a variety of 3,4-dihydropyrrolo[2,1- a ]isoquinolines and α,β-unsaturated aldehydes in the absence of catalyst in good yields under microwave irradiation, is reported.

Authors
Matveeva M.D. 1 , Borisova T.N. 1 , Titov A.A. 1 , Anikina L.V.2 , Dyachenko S.V. 1 , Astakhov G.S. 1 , Varlamov A.V. 1 , Voskressensky L.G. 1
Journal
Synthesis
Number of issue
23
Language
English
Pages
5251-5257
Status
Published
Link
External link
DOI
10.1055/s-0036-1588486
Volume
49
Year
2017
Organizations
  • 1 Peoples' Friendship University of Russia (RUDN University), Mikluho-Maklaya St., 6, Moscow, 117198, Russian Federation
  • 2 Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Russian Federation
Keywords
aldehydes; cytotoxic activity; dihydroisoquinolines; domino reaction; microwave irradiation
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/5138/
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