Identification and quantitative determination of active pharmaceutical ingredients in suppositories by a combination of 1H NMR spectroscopy and desorption mass spectrometry

A fast, highly sensitive, and precise procedure was proposed for the identification and determination of the composition of suppositories, which are dosage forms of drugs in a lipophilic base, using a combination of quantitative 1H NMR spectroscopy and desorption mass spectrometry methods. © 2014 Springer Science+Business Media New York.

Authors
Kalabin G.A. 1 , Goryainov S.V. 1 , Ivlev V.A. 1 , Niftullaev F.Yu. 1 , Abramovich R.A. 1
Journal
Russian Chemical Bulletin
Number of issue
8
Language
English
Pages
1848-1855
Status
Published
Link
External link
DOI
10.1007/s11172-014-0675-7
Volume
63
Year
2014
Organizations
  • 1 Peoples' Friendship University of Russia, 6 ul. Miklukho-Maklaya, Moscow, 117198, Russian Federation
Keywords
active pharmaceutical ingredients; desorption mass spectrometry; nuclear magnetic resonance spectroscopy; quantitative analysis; suppositories
Date of creation
19.10.2018
Date of change
13.05.2021
Short link
https://repository.rudn.ru/en/records/article/record/4831/
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