Preparation and Investigation of Tabletted Medicinal Formulations of a Solid Dispersion of Rutin

Asolid dispersion of rutin based on polyvinylpyrrolidone had greater solubility than rutin substance, which is valuable for creating effective formulations based on this material. We describe here the preparation of tableted medicinal formulations of a solid dispersion of rutin prepared by direct pressing and moist granulation. A comparative analysis of the resulting granulates and tablets in terms of the main physical-technical characteristics is presented. © 2015, Springer Science+Business Media New York.

Authors
Krasnyuk I.I.Jr. , Koval’skii I.V.1 , Nikulina O.I.1 , Belyatskaya A.V.1 , Krasnyuk I.I.1 , Kharitonov Y.Y.1 , Grikh V.V.1 , Korol’ L.A.1 , Obidchenko Y.A. 2 , Vorob’ev A.N.2
Editors
-
Publisher
-
Number of issue
7
Language
English
Pages
481-485
Status
Published
Department
-
Number
-
Volume
49
Year
2015
Organizations
  • 1 First I. M. Sechenov Moscow State Medical University, Ministry of Health of the Russian Federation, Moscow, Russian Federation
  • 2 Collaborative Resource Center (Scientific and Educational Center), Russian University of the Friendship of the Peoples, Moscow, Russian Federation
Keywords
mechanism of action; properties; rutin; rutin aglycone
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/4500/