International Journal on Minority and Group Rights. Vol. 10. 2003. P.. 203-220
Direct reductive coupling of indoles to nitrostyrenes en route to (indol-3-yl)acetamides
A highly efficient one-pot method for the reductive coupling of indoles to nitrostyrenes in polyphosphoric acid doped with PCl3 was developed. This method allows direct and expeditious access to primary (indol-3-yl)acetamides, interesting as anti-cancer drug candidates. © 2016 The Royal Society of Chemistry.
Authors
Aksenov A.V. 1 , Aksenov N.A. 1, 2 , Dzhandigova Z.V. 1 , Aksenov D.A. 1 , Voskressensky L.G. 2 , Nenajdenko V.G. 3 , Rubin M. 1, 4
Journal
Issue number
96
Language
English
Pages
93881-93886
State
Published
Link
Volume
6
Year
2016
Organizations
- 1 Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., Stavropol, 355009, Russian Federation
- 2 Department of Organic Chemistry, People's Friendship University of Russia, 6 Miklukho-Maklaya St., Moscow, 117198, Russian Federation
- 3 Department of Chemistry, Lomonosov Moscow State University, Moscow, 119899, Russian Federation
- 4 Department of Chemistry, University of Kansas, 1251 Wescoe Hall Dr., Lawrence, KS 66045-7582, United States
Keywords
Anticancer drug; En-route; One-pot method; Polyphosphoric acids; Reductive couplings
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