Rational design of an efficient one-pot synthesis of 6H-pyrrolo[2,3,4- gh] perimidines in polyphosphoric acid

Several highly efficient one-pot synthetic protocols were developed, enabling polyphosphoric acid-activated nitroalkanes to act as electrophiles in reactions with aminonapthalenes. The featured methods allow for the single step assembly of polyheterocyclic aromatic derivatives of 6H-pyrrolo[2,3,4-gh]perimidine scaffold in high yields. © 2016 The Royal Society of Chemistry.

Authors
Aksenov A.V.1 , Aksenov N.A. 1, 2 , Ovcharov D.S.1 , Aksenov D.A.1 , Griaznov G.1 , Voskressensky L.G. 2 , Rubin M.1, 3
Journal
RSC Advances
Number of issue
85
Language
English
Pages
82425-82431
Status
Published
Link
External link
DOI
10.1039/c6ra17269e
Volume
6
Year
2016
Organizations
  • 1 Department of Chemistry, North Caucasus Federal University, 1a Pushkin St., Stavropol, 355009, Russian Federation
  • 2 Department of Organic Chemistry, People's Friendship University of Russia, 6 Miklukho-Maklaya St., Moscow, 117198, Russian Federation
  • 3 Department of Chemistry, University of Kansas, 1251 Wescoe Hall Dr., Lawrence, KS 66045-7582, United States
Keywords
Aromatic derivatives; Electrophiles; Nitroalkanes; One-pot synthesis; Polyphosphoric acids; Rational design; Single-step; Synthetic protocols; Scaffolds
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/4283/
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