Russian Journal of Physical Chemistry A.
Vol. 90.
2016.
P. 1137-1142
Expression of Bax Protein and Morphological Changes in the Myocardium in Experimental Acute Pressure Overload of the Left Ventricle
The expression of Bax protein, marker of intracellular pathway of apoptosis initiation, in viable left ventricular cardiomyocytes and morphological changes in the myocardium in acute pressure overload of the left ventricle were studied in experiment on male rabbits. The content of Bax protein in the cardiomyocyte cytoplasm decreased, this indicating that the mitochondrial pathway was not involved in the realization of the apoptotic program. This decrease was associated with manifest destructive changes in the left ventricular myocardium. © 2016, Springer Science+Business Media New York.
Authors
Publisher
New York Consultants BureauSpringer / Автономная некоммерческая организация Издательство Российской академии медицинских наук
Number of issue
2
Language
English
Pages
312-315
Status
Published
Link
Volume
161
Year
2016
Organizations
- 1 Department of Pathology and Pathological Physiology, Moscow, Russian Federation
- 2 Department of Biology and Common Genetics, Medical Institute, Russian, University of Peoples’ Friendship, Moscow, Russian Federation
Keywords
acute left ventricular overload; apoptosis; Bax; cardiomyocyte; myocardium
Date of creation
19.10.2018
Date of change
19.10.2018
Share
Other records
Differential Equations.
Vol. 52.
2016.
P. 749-760