Effects of L-lysine-α-oxidase from trichoderma in vitro experiments on the model of viruses as sindbis, tick-borne encephalitis, west nile, tahyna and dhori

For the first time we studied the effect of the anticancer drug L-lysine-α-oxidase, obtained from culture liquid of Trichoderma harzianum Rifai F-180. In vitro experiments we established the high activity of L-lysine-α-oxidase in a model of tick-borne encephalitis and the lack of activity against viruses Sindbis, West Nile, Tahyna and Dhori. © RJPT All right reserved.

Authors
Larichev V.F. 1 , Smirnova I.P. 2 , Syatkin S.P. 2 , Myandina G.I. 2 , Chibisov S.M. 2 , Ryskina Е.А. 2
Journal
Research Journal of Pharmacy and Technology
Number of issue
3
Language
English
Pages
765-768
Status
Published
Link
External link
DOI
10.5958/0974-360X.2017.00143.3
Volume
10
Year
2017
Organizations
  • 1 Federal State Budgetary Institution “Research Institute of Epidemiology and Microbiology named after Honorable Academician N. F. Gamaleya”, 16 Gamalei Str, Moscow, Russian Federation
  • 2 Medical Department of Medical Institute of Peoples’ Friendship University of Russia, 3 Ordzhonikidze Str., Moscow, Russian Federation
Keywords
Antiviral activity; Arboviruses; Cytopathic effect; L-lysine-α-oxidase; Tick-borne encephalitis
Date of creation
19.07.2019
Date of change
19.07.2019
Short link
https://repository.rudn.ru/en/records/article/record/39091/
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