Multicomponent synthesis and molecular structure of 3-amino-2-aroyl(alkoxycarbonyl, arylcarbamoyl)-4-aryl(hetaryl)-5-arylcarbamoyl-6-methylthieno[2,3-b]pyridines

[Figure not available: see fulltext.] A new, effective method has been developed for the synthesis of functionalized thieno[2,3-b]pyridines by multicomponent condensation reactions of aromatic and heteroaromatic aldehydes, cyanothioacetamide, acetoacetanilides, and alkylating agents containing activated methylene groups. The structures of 3-amino-2-benzoyl-4-(furan-2-yl)-6-methyl-N-phenylthieno[2,3-b]pyridine-5-carboxamide, 3-amino-N2-(4-bromophenyl)-N5-(4-chlorophenyl)-6-methyl-4-(3-methylthiophen-2-yl)thieno[2,3-b]pyridine-2,5-dicarboxamide, and 3-amino- 4-(2-chlorophenyl)-N-(4-chlorophenyl)-6-methyl-2-(4-methylbenzoyl)thieno[2,3-b]pyridine-5-carboxamide were studied by X-ray structural analysis. © 2019, Springer Science+Business Media, LLC, part of Springer Nature.

Authors
Dyachenko I.V.1 , Dyachenko V.D.1 , Dorovatovskii P.V. 2 , Khrustalev V.N. 3 , Nenajdenko V.G. 4
Editors
-
Publisher
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Number of issue
4-5
Language
English
Pages
442-447
Status
Published
Department
-
Number
-
Volume
55
Year
2019
Organizations
  • 1 Luhansk Taras Shevchenko National University, 2 Oboronna St., Luhansk, 91011, Ukraine
  • 2 National Research Center “Kurchatov Institute”, 1 Akademika Kurchatova Sq., Moscow, 123182, Russian Federation
  • 3 RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russian Federation
  • 4 Lomonosov Moscow State University, 1-3 Leninskie Gory, Moscow, 119991, Russian Federation
Keywords
acetoacetanilides; alkylating reagents; aromatic aldehydes; cyanothioacetamide; thieno[2,3-b]pyridines; X-ray structural analysis
Date of creation
19.07.2019
Date of change
19.07.2019
Short link
https://repository.rudn.ru/en/records/article/record/38626/