RPC 2018 - Proceedings of the 3rd Russian-Pacific Conference on Computer Technology and Applications.
Institute of Electrical and Electronics Engineers Inc..
2018.
Gold-catalyzed post-Ugi alkyne hydroarylation for the synthesis of 2-quinolones
A series of propargylamides containing an electron-rich benzene ring was prepared through the Ugi reaction of 3,5-dimethoxy-aniline with various propiolic acids, aldehydes and isocyanides. Subjecting these adducts to a gold-catalyzed intramolecular alkyne hydroarylation process allowed to efficiently construct the 2-quinolone core bearing a branched substituent on the nitrogen atom. © 2018 Du et al.
Authors
Du X.1
,
Huang J.1
,
Nechaev A.A.2
,
Yao R.1
,
Gong J.1
,
Van Der Eycken E.V. ,
Pereshivko O.P.1
,
Peshkov V.A.1,
4
Publisher
Beilstein-Institut Zur Forderung der Chemischen Wissenschaften
Language
English
Pages
2572-2579
Status
Published
Link
Volume
14
Year
2018
Organizations
- 1 College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Dushu Lake Campus, Suzhou, 215123, China
- 2 Laboratory for Organic and Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, University of Leuven (KU Leuven), Celestijnenlaan 200F, Leuven, 3001, Belgium
- 3 Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya street, Moscow, 117198, Russian Federation
- 4 Department of Chemistry, School of Science and Technology, Nazarbayev University, 53 Kabanbay Batyr Ave, Block 7, Astana, 010000, Kazakhstan
Keywords
2-quinolones; Gold catalysis; Hydroarylation; Ugi reaction
Date of creation
04.02.2019
Date of change
04.02.2019
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Materials.
MDPI AG.
Vol. 11.
2018.