Оценка эквивалентности антигипертензивных лекарственных средств по тесту «Растворение»

EQUIVALENCE ESTIMATES FOR ANTIHYPERTENSIVE DRUGS BY DISSOLUTION TES

The study was aimed to assess the equivalence of valsartan tablets of different manufacturers using in vitro dissolution study. Materials and methods: The dissolution was carried out using the apparatus II.Results: A similarity factor (f2) was employed. Samples with pH 1.2 and 4.5 showed the value more than 50%. Samples in pH 6.8 attained more than 85% dissolution within 15 minutes. Сonclusions: Studied tablets are equivalent to original drug.

Authors
Бригас Е.Р. 1 , Успенская Е.В. 1 , Писарев В.В. 1
Conference proceedings
SCIENCE4HEALTH 2016. Clinical and Theoretical Features of Modern Medicine: MATERIALS OF VII INTERNATIONAL SCIENTIFIC CONFERENCE. MOSCOW, 12 – 15 APRIL 2016 Download
Publisher
РУДН
Language
Russian
Pages
60-60
Status
Published
Year
2016
Organizations
  • 1 Peoples Friendship University of Russia
Keywords
poster
Date of creation
30.10.2018
Date of change
06.06.2019
Short link
https://repository.rudn.ru/en/records/article/record/31876/
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