The first example of tetrahydrothieno[3,2-d]azocines synthesis

Voskressensky L.G. ¹ , Listratova A.V. ¹ , Borisova T.N. ¹ , Kovaleva S.A. ¹ , Borisov R.S. ¹ , Varlamov A.V. ¹

Tetrahedron

45

English

10443-10452

Published

External link

10.1016/j.tet.2008.08.034

64

2008

• ¹ Organic Chemistry Department, Russian Peoples Friendship University, 6, Miklukho-Maklaia Street, Moscow, 117198, Russian Federation

3 ethyl 7,8 dimethyl 2 (acetylamino) 6 benzyl 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,7,8 tricarboxylate; 3 ethyl 7,8 dimethyl 2 (acetylamino) 6 ethyl 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,7,8 tricarboxylate; 3 ethyl 7,8 dimethyl 2 (acetylamino) 6 methyl 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,7,8 tricarboxylate; 3 ethyl 7,8 dimethyl 6 benzyl 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,7,8 tricarboxylate; 3 ethyl 7,8 dimethyl 6 ethyl 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,7,8 tricarboxylate; 3 ethyl 7,8 dimethyl 6 isopropyl 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,7,8 tricarboxylate; 3 ethyl 7,8 dimethyl 6 methyl 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,7,8 tricarboxylate; 3 ethyl 8 methyl 2 (acetylamino) 6 benzyl 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,8 dicarboxylate; 3 ethyl 8 methyl 2 (acetylamino) 6 ethyl 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,8 dicarboxylate; 3 ethyl 8 methyl 2 (acetylamino) 6 isopropyl 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,8 dicarboxylate; 3 ethyl 8 methyl 2 (acetylamino) 6 methyl 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,8 dicarboxylate; 3 ethyl 8 methyl 6 benzyl 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,8 dicarboxylate; 3 ethyl 8 methyl 6 ethyl[(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,8 dicarboxylate; 3 ethyl 8 methyl 6 isopropyl 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,8 dicarboxylate; 3 ethyl 8 methyl 6 methyl 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3,8 dicarboxylate; azocine derivative; dimethyl 2 [[2 [5 (acetylamino) 4 (ethoxycarbonyl) 2 (methoxymethyl) 3 thienyl]ethyl](methyl)amino]but 2 enedioate; ethyl 6 benzyl 8 [(4 methylphenyl)sulphonyl] 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3 carboxylate; ethyl 6 ethyl 8 [(4 methylphenyl)sulphonyl] 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3 carboxylate; ethyl 6 isopropyl [(4 methylphenyl)sulphonyl] 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3 carboxylate; ethyl 6 methyl 8 [(4 methylphenyl)sulphonyl] 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3 carboxylate; ethyl 8 acetyl 2 (acetylamino) 6 benxyl 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3 carboxylate; ethyl 8 acetyl 2 (acetylamino) 6 ethyl 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3 carboxylate; ethyl 8 acetyl 2 (acetylamino) 6 isopropyl 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3 carboxylate; ethyl 8 acetyl 6 benzyl 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3 carboxylate; ethyl 8 acetyl 6 ethyl 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3 carboxylate; ethyl 8 acetyl 6 isopropyl 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3 carboxylate; ethyl 8 acetyl 6 methyl 2 [(trifluoroacetyl)amino] 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3 carboxylate; ethyl 8 acetyl(acetylamino) 6 methyl 4,5,6,9 tetrahydrothieno[3,2 d]azocine 3 carboxylate; tetrahydrothieno[3,2 d]azocine derivative; unclassified drug; article; carbon nuclear magnetic resonance; chemical modification; chemical reaction; chemical structure; crystal structure; one pot synthesis; priority journal; proton nuclear magnetic resonance; X ray crystallography

19.10.2018

27.02.2021

https://repository.rudn.ru/en/records/article/record/3043/