Silica-sulfuric acid: a highly efficient catalyst for the synthesis of imidazo[1,2-a]pyridines using trimethysilyl cyanide or cyanohydrins

This Letter describes a novel synthetic approach towards imidazo[1,2-a]pyridines via a three-component condensation using trimethylsilyl cyanide (TMSCN) or cyanohydrins as the source of CN- ions and silica-sulfuric acid as the catalyst. © 2009 Elsevier Ltd. All rights reserved.

Authors
Polyakov A.I.1 , Eryomina V.A.1 , Medvedeva L.A.1 , Tihonova N.I.1 , Listratova A.V. 2 , Voskressensky L.G. 2
Journal
Tetrahedron Letters
Publisher
Elsevier Ltd
Number of issue
30
Language
English
Pages
4389-4393
Status
Published
Link
External link
DOI
10.1016/j.tetlet.2009.05.080
Volume
50
Year
2009
Organizations
  • 1 New Chemistry Horizons Laboratories Ltd, PO Box 130, Moscow, 115522, Russian Federation
  • 2 Organic Chemistry Department, Russian Peoples' Friendship University, 6, Miklukho-Maklaya St, Moscow, 117198, Russian Federation
Keywords
Catalyst; Cyanides; Cyanohydrins; Imidazopyridines; Multicomponent condensation
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/2941/
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