Russian Journal of General Chemistry. Vol. 79. 2009. P.. 1987-1997
A novel alkyne-induced recyclization of 4-hydroxymethyl or 4-formyl-1H-2,3-dihydroisoindoles-an effective pathway to substituted isobenzofurans
2-Alkyl or 2-benzyl-substituted 4-hydroxymethyl(formyl)isoindoles readily react with electron-deficient alkynes undergoing intramolecular cyclization to produce 1-aminomethyl-substituted isobenzofurans in good yields. © 2009 Elsevier Ltd. All rights reserved.
Authors
Voskressensky L.G. 1 , Kulikova L.N. 1 , Kleimenov A. 1 , Guranova N. 1 , Borisova T.N. 1 , Varlamov A.V. 1
Journal
Publisher
Elsevier Ltd
Issue number
34
Language
English
Pages
4851-4853
State
Published
Link
Volume
50
Year
2009
Organizations
- 1 Organic Chemistry Department, Russian Peoples' Friendship University, 6, Miklukho-Maklaya St, Moscow, 117198, Russian Federation
Keywords
4 formyl 1h 2,3 dihydroisoindole derivative; alkyne derivative; isobenzofuran derivative; isoindole derivative; unclassified drug; article; chemical reaction; chemical structure; cyclization; synthesis; temperature measurement
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Other records
Bulletin of Experimental Biology and Medicine. Vol. 147. 2009. P.. 397-399