Essential hypertension, dementia, and antihypertensive therapy in geriatric patients

The review summarizes the current views on the pathogenesis of dementia and the significance of blood pressure levels for its development. The present status of the prevention of cognitive disorders and dementia is detailed in the use of antihypertensive therapy: there are the data of prospective cohort studies of the impact of antihypertensive therapy on the risk of dementia, the results of placebo-controlled studies in the groups of elderly and senile patients with a history of cerebrovascular complications, and the data of meta-analyses of studies. As for cognitive function, the effects of different classes of the currently available antihypertensive agents, such as diuretics, calcium antagonists, angiotensin-converting enzyme inhibitors, and angiotensin II type 1 receptor antagonists, are analyzed.

Authors
Kobalava Zh.D. 1 , Kotovskaya Yu.V. 1 , Tyulkina E.E.2
Number of issue
10
Language
Russian
Pages
64-70
Status
Published
Volume
81
Year
2009
Organizations
  • 1 Russian University of People's Friendship, Russian Federation
  • 2 City Clinical Hospital Sixty-Four, Moscow, Russian Federation
Keywords
Angiotensin II type 1 receptor antagonists; Angiotensin-converting enzyme inhibitors; Antihypertensive therapy; Calcium antagonists; Cognitive junction; Dementia; Diuretics; Essential hypertension
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/2873/
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