Boletim da Sociedade Paranaense de Matematica. Vol. 28. 2010. P.. 67-77
High-performance liquid chromatography coupled to mass spectrometry for studying new pharmaceutical entities
The review covers the aspects of the use of high-performance liquid chromatography coupled to mass spectrometry for studying new pharmaceutical entities. Attention is paid mainly to pharmacokinetic investigations. Different methods of sample preparation and approaches to minimize the duration of the analysis are discussed. © 2010, Pleiades Publishing, Ltd.
Authors
Chernetsova E.S. 1 , Koryakova A.G. 2
Issue number
14
Language
English
Pages
1436-1445
State
Published
Link
Volume
65
Year
2010
Organizations
- 1 Peoples Friendship University, ul. Miklukho-Maklaya 8/2, Moscow, 117198, Russian Federation
- 2 Chemical Diversity Research Institute, ul. Rabochaya 2a, Khimki, Moscow oblast, 141400, Russian Federation
Keywords
drug candidate; HPLC/MS; pharmacokinetics; quantification
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Experimental and Clinical Pharmacology. Vol. 73. 2010. P.. 17-20