High-performance liquid chromatography coupled to mass spectrometry for studying new pharmaceutical entities

The review covers the aspects of the use of high-performance liquid chromatography coupled to mass spectrometry for studying new pharmaceutical entities. Attention is paid mainly to pharmacokinetic investigations. Different methods of sample preparation and approaches to minimize the duration of the analysis are discussed. © 2010, Pleiades Publishing, Ltd.

Authors
Chernetsova E.S. 1 , Koryakova A.G.2
Number of issue
14
Language
English
Pages
1436-1445
Status
Published
Volume
65
Year
2010
Organizations
  • 1 Peoples Friendship University, ul. Miklukho-Maklaya 8/2, Moscow, 117198, Russian Federation
  • 2 Chemical Diversity Research Institute, ul. Rabochaya 2a, Khimki, Moscow oblast, 141400, Russian Federation
Keywords
drug candidate; HPLC/MS; pharmacokinetics; quantification
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/2662/
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