Determination of drugs and drug-like compounds in different samples with direct analysis in real time mass spectrometry

Direct analysis in real time (DART), a relatively new ionization source for mass spectrometry, ionizes small-molecule components from different kinds of samples without any sample preparation and chromatographic separation. The current paper reviews the published data available on the determination of drugs and drug-like compounds in different matrices with DART-MS, including identification and quantitation issues. Parameters that affect ionization efficiency and mass spectra composition are also discussed. © 2011 Wiley Periodicals, Inc.

Authors
Chernetsova E.S. 1 , Morlock G.E.2
Number of issue
5
Language
English
Pages
875-883
Status
Published
Volume
30
Year
2011
Organizations
  • 1 Research and Educational Center, Peoples' Friendship University of Russia, Bldg. 8/2, Miklucho-Maklay st., 117198 Moscow, Russian Federation
  • 2 Institute of Food Chemistry, University of Hohenheim, Garbenstr. 28, 70599 Stuttgart, Germany
Keywords
ambient mass spectrometry; DART; direct analysis in real time; drugs; identification; quantitation
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/2505/