Synthesis of tetrazolodiazepines by a five-centered four-component azide Ugi reaction. Scope and limitations

Tetrazolo[1,5-a][1,4]benzodiazepines were obtained by an efficient azide five-centered four-component Ugi reaction, which used ketones, sodium azide, ammonium chloride, and the corresponding isonitrile. Scope and limitations of this multi-component reaction were considered. © 2012 Springer Science+Business Media New York.

Authors
Borisov R.S. 1 , Polyakov A.I.2 , Medvedeva L.A.2 , Guranova N.I. 3 , Voskressensky L.G. 3
Journal
Russian Chemical Bulletin
Number of issue
8
Language
English
Pages
1609-1615
Status
Published
Link
External link
DOI
10.1007/s11172-012-0214-3
Volume
61
Year
2012
Organizations
  • 1 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences, 29 Leninsky prosp., 119991 Moscow, Russian Federation
  • 2 N. N. Blokhin Russian Cancer Scientific Center, Russian Academy of Medical Sciences, 24 Kashirskoe shosse, 115478 Moscow, Russian Federation
  • 3 Peoples' Frendship University of Russia, 6 ul. Miklukho-Maklaya, 117198 Moscow, Russian Federation
Keywords
1,4-benzodiazepines; azide; isonitriles; tetrazolodiazepines; Ugi reaction
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/2285/
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