Recyclization of benzofuropyridines by the action of activated alkynes in the synthesis of spiro[benzofuropyridines], representatives of a new class of acetylcholinesterase inhibitors

A study was carried out on the domino transformations of tetrahydrobenzofuro[2,3-c]pyridines and tetrahydrobenzofuro[3,2-c]pyridines by the action of activated alkynes in methanol and acetonitrile. This reaction is a new method for the synthesis of spiro[benzofuropyridines] showing acetylcholinesterase inhibition activity. © 2013 Springer Science+Business Media New York.

Authors
Voskressensky L.G. 1 , Kovaleva S.A. 1 , Borisova T.N. 1 , Eresko A.B.2 , Tolkunov V.S.2 , Tolkunov S.V.2 , Listratova A.V. 1 , De Candia M. , Altomare C.3 , Varlamov A.V. 1
Journal
Chemistry of Heterocyclic Compounds
Publisher
Латвийский институт органического синтеза Латвийской академии наук / Springer New York Consultants Bureau
Number of issue
6
Language
English
Pages
930-940
Status
Published
Link
External link
DOI
10.1007/s10593-013-1328-8
Volume
49
Year
2013
Organizations
  • 1 Peoples' Friendship University of Russia, 6 Miklukho-Maklaya St., Moscow 117198, Russian Federation
  • 2 L. M. Litvinenko Institute of Physical Organic and Coal Chemistry, 70 R. Luxemburg St., Donetsk 83114, Ukraine
  • 3 Università Degli Studi di Bari, Via E. Orabona 4, Bari I-70125, Italy
Keywords
acetylcholinesterase inhibition; activated alkynes; domino reactions; ring expansion; tetrahydrobenzofuropyridines
Date of creation
19.10.2018
Date of change
27.02.2021
Short link
https://repository.rudn.ru/en/records/article/record/2018/
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