A simple, three-component synthesis of 2-aminothiazoles using trimethylsilyl isothiocyanate

The first multicomponent, solution-phase protocol to prepare privileged 2-aminothiazoles from α-bromocarbonyl compounds and amines (aromatic and aliphatic) using commercially available trimethylsilyl isothiocyanate is described. © 2013 Elsevier Ltd. All rights reserved.

Authors
Golubev V. 1 , Zubkov F. 1 , Krasavin M.2
Journal
Tetrahedron Letters
Publisher
Elsevier Ltd
Number of issue
36
Language
English
Pages
4844-4847
Status
Published
Link
External link
DOI
10.1016/j.tetlet.2013.06.102
Volume
54
Year
2013
Organizations
  • 1 Peoples' Friendship University of Russia, 6 Miklukho-Maklaya St., Moscow, Russian Federation
  • 2 Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD 4111, Australia
Keywords
2-Aminothioazoles; Combinatorial chemistry; Multicomponent reactions; Parallel solution-phase synthesis; Privileged structures
Date of creation
19.10.2018
Date of change
13.08.2021
Short link
https://repository.rudn.ru/en/records/article/record/2011/
Share

Other records