Gold complexes containing (non)protonated oligopyridines - unexpected results in cancer drug research

Two novel gold(<jats:sc>iii</jats:sc>) complexes with doubly protonated forms of phenanthrolines, (neocH<jats:sub>2</jats:sub>)[AuCl<jats:sub>4</jats:sub>]·Cl (1) and (1,7-phenH<jats:sub>2</jats:sub>)[AuCl<jats:sub>4</jats:sub>]·NO<jats:sub>3</jats:sub> (2), were synthesized using the phenanthrolines.

Authors
Koshenskova Kseniya A. 1 , Bardina Elena E. 2 , Makotchenko Eugeniya V. 2 , Kharlamova Viktoria Yu. 2 , Mironov Igor V. 2 , Bekker Olga B. 3 , Treshalina Helen M. 4 , Sokolova Darina V. 4 , Pokrovsky Vadim S. 4, 5 , Borodin Eugenii A. 6 , Kotel'nikov Danil D. 6 , Belyaev Danila V. 7, 8 , Vakhrusheva Diana V. 7 , Krasnoborova Svetlana Yu. 7 , Rusinov Gennadii L. 7, 8 , Timofeev Eduard A. 9 , Leusova Nataliya Yu. 9 , Kiskin Mikhail A. 1 , Gushchin Artem L. 2 , Eremenko Igor L. 1 , Lutsenko Irina A. 1, 5
Journal
New Journal of Chemistry
Publisher
Royal Society of Chemistry
Language
English
State
Published
Link
External link
DOI
10.1039/D5NJ02110C
Year
2025
Organizations
  • 1 N.S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Leninsky Prosp. 31, 119991 GSP-1 Moscow, Russian Federation
  • 2 A. V. Nikolaev Institute of Inorganic Chemistry, Siberian Branch of Russian Academy of Sciences, Acad. Lavrentiev Ave., 3, Novosibirsk, 630090, Russian Federation
  • 3 N. I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Gubkina, 3, 119333, Moscow, Russian Federation
  • 4 Federal State Budgetary Institution “N. N. Blokhin National Medical Research Center of Oncology” of the Ministry of Health of the Russion Federation, Kashirskoe Shosse, 24, Moscow, 115478, Russian Federation
  • 5 RUDN University, Miklukho-Maklaya 6, Moscow, 117198, Russian Federation
  • 6 Amur State Medical Academy, Ministry of Health of the Russian Federation, Gorkogo str., 95, Blagoveshchensk, 675001, Russian Federation
  • 7 National Medical Research Center of Phthisiopulmononlogy and Infectious Diseases of Ministry of Health of the Russian Federation, 22nd Partsyezda str., 50, Ekaterinburg, 620039, Russian Federation
  • 8 I. Ya. Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences, S. Kovalevskoy Str., 22, Ekaterinburg 620137, Russian Federation
  • 9 Institute of Geology and Nature Management, Far Eastern Branch, Russian Academy of Sciences, per. Relochnyi, 3, Blagoveshchensk, 675000, Russian Federation
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