Gold complexes containing (non)protonated oligopyridines - unexpected results in cancer drug research

Two novel gold(iii) complexes with doubly protonated forms of phenanthrolines, (neocH2)[AuCl4]·Cl (1) and (1,7-phenH2)[AuCl4]·NO3 (2), were synthesized using the phenanthrolines.

Authors
Koshenskova Kseniya A.1 , Bardina Elena E.2 , Makotchenko Eugeniya V.2 , Kharlamova Viktoria Yu.2 , Mironov Igor V.2 , Bekker Olga B.3 , Treshalina Helen M.4 , Sokolova Darina V.4 , Pokrovsky Vadim S. 4, 5 , Borodin Eugenii A.6 , Kotel'nikov Danil D.6 , Belyaev Danila V.7, 8 , Vakhrusheva Diana V.7 , Krasnoborova Svetlana Yu.7 , Rusinov Gennadii L.7, 8 , Timofeev Eduard A.9 , Leusova Nataliya Yu.9 , Kiskin Mikhail A.1 , Gushchin Artem L.2 , Eremenko Igor L.1 , Lutsenko Irina A.1, 5
Publisher
Royal Society of Chemistry
Language
English
Status
Published
Year
2025
Organizations
  • 1 N.S. Kurnakov Institute of General and Inorganic Chemistry of the Russian Academy of Sciences, Leninsky Prosp. 31, 119991 GSP-1 Moscow, Russian Federation
  • 2 A. V. Nikolaev Institute of Inorganic Chemistry, Siberian Branch of Russian Academy of Sciences, Acad. Lavrentiev Ave., 3, Novosibirsk, 630090, Russian Federation
  • 3 N. I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Gubkina, 3, 119333, Moscow, Russian Federation
  • 4 Federal State Budgetary Institution “N. N. Blokhin National Medical Research Center of Oncology” of the Ministry of Health of the Russion Federation, Kashirskoe Shosse, 24, Moscow, 115478, Russian Federation
  • 5 RUDN University, Miklukho-Maklaya 6, Moscow, 117198, Russian Federation
  • 6 Amur State Medical Academy, Ministry of Health of the Russian Federation, Gorkogo str., 95, Blagoveshchensk, 675001, Russian Federation
  • 7 National Medical Research Center of Phthisiopulmononlogy and Infectious Diseases of Ministry of Health of the Russian Federation, 22nd Partsyezda str., 50, Ekaterinburg, 620039, Russian Federation
  • 8 I. Ya. Postovsky Institute of Organic Synthesis of the Ural Branch of the Russian Academy of Sciences, S. Kovalevskoy Str., 22, Ekaterinburg 620137, Russian Federation
  • 9 Institute of Geology and Nature Management, Far Eastern Branch, Russian Academy of Sciences, per. Relochnyi, 3, Blagoveshchensk, 675000, Russian Federation
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