ctDNA transiting into urine is ultrashort and facilitates noninvasive liquid biopsy of HPV+ oropharyngeal cancer

Bhambhani Chandan⁹ , Kang Qing⁹ , Hovelson D.H. ^{10, 11} , Sandford Erin⁹ , Olesnavich Mary⁹ , Dermody S.M.¹² , Wolfgang Jenny⁹ , Tuck K.L.⁹ , Brummel Collin¹² , Bhangale A.D.¹² , He Kuang⁹ , Gutierrez M.G.¹³ , Lindstrom R.H.⁹ , Liu Chia-Jen¹¹ , Tuck Melissa⁹ , Kandarpa Malathi⁹ , Mierzwa Michelle , Casper Keith¹² , Prince M.E.¹² , Krauss J.C.⁹ , Talpaz Moshe⁹ , Henry N.L.⁹ , Giraldez M.D.⁹ , Ramnath Nithya⁹ , Tomlins S.A.¹¹ , Swiecicki P.L.⁹ , Brenner J.C.¹² , Tewari Muneesh⁹

JCI Insight

6

English

Published

9

2024

• ¹ Department of Internal Medicine, Division of Hematology/Oncology,
• ² Department of Computational Medicine & Bioinformatics,
• ³ Michigan Center for Translational Pathology,
• ⁴ Department of Otolaryngology,
• ⁵ Department of Internal Medicine,
• ⁶ Department of Pathology,
• ⁷ Department of Radiation Oncology, and
• ⁸ Rogel Cancer Center, University of Michigan, Ann Arbor, Michigan, USA.
• ⁹ Institute of Biomedicine of Seville (IBiS), Hospital Universitario Virgen del Rocío, Consejo Superior de Investigaciones Científicas, University of Seville, Seville, Spain.
• ¹⁰ Department of Urology,
• ¹¹ Department of Pharmacology,
• ¹² Center for Computational Biology and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.
• ¹³ Department of Biomedical Engineering, and