ANTICANCER EFFECT OF POLYAMINE ANALOGUES

Polyamine exchange is considered to be a target for anticancer drug design. The search of biologically active molecules is carried out among polyamine analogues of different chemical classes. The most promising can be those ones which cause polyamine depletion and/or cytotoxic agents generation via polyamine oxidation activation.

Authors
Hilal Abdullah 1 , Ulyumdzhieva V.E. 1
Conference proceedings
Современная парадигма научного знания: актуальность и перспективы: сборник статей по материалам Пятой международной научно-практической конференции. Москва, 05 апреля 2017 г. (Modern Paradigm of the Scientific Knowledge: Actuality and Prospects: proceedings of the V International Multidisciplinary Scientific and Practical Conference in Foreign Languages)
Publisher
Языки Народов Мира
Language
English
Pages
157-158
State
Published
Year
2017
Organizations
  • 1 RUDN
Keywords
polyamine; cell proliferation; cell differentiation; drug design; cancer; putrescine; spermidine; spermine; polyamine analogues
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