ANTICANCER EFFECT OF POLYAMINE ANALOGUES

Polyamine exchange is considered to be a target for anticancer drug design. The search of biologically active molecules is carried out among polyamine analogues of different chemical classes. The most promising can be those ones which cause polyamine depletion and/or cytotoxic agents generation via polyamine oxidation activation.

Authors
Hilal Abdullah 1 , Ulyumdzhieva V.E. 1
Conference proceedings
Modern Paradigm of the Scientific Knowledge: Actuality and Prospects: proceedings of the V International Multidisciplinary Scientific and Practical Conference in Foreign Languages
Publisher
Языки Народов Мира
Language
English
Pages
157-158
Status
Published
Year
2017
Organizations
  • 1 RUDN
Keywords
polyamine; cell proliferation; cell differentiation; drug design; cancer; putrescine; spermidine; spermine; polyamine analogues
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