On some morphofunctional bases of formation of 'hypertension heart'

Morphofunctional analysis of the work of the heart in the time course of experimental arterial hypertension showed that three pathogenetic stages could be clearly distinguished in the formation of 'hypertension heart': the stage of formation (1st-4th week) when marked signs of overloading are noted in the myocardium and compensatory-adaptative changes begin to develop; the stage of compensation (6th-10th week) when the process is stabilized and adaptative changes are marked in the heart muscle, particularly myocardial hypertrophy; and the stage of decompensation (22nd-52nd week) when destructive changes develop in the myocardium and its contractile capacity weakens.

Authors
Number of issue
5
Language
Russian
Pages
35-41
Status
Published
Volume
44
Year
1982
Organizations
  • 1 Patrice Lumumba Univ. Friendship Peoples, Moscow
Keywords
animal experiment; cardiovascular system; heart; heart left ventricle hypertrophy; histology; hypertension; mammal; animal; article; blood pressure; cardiomegaly; heart contraction; heart muscle; hypertension; male; pathology; pathophysiology; rabbit; time; ultrastructure; Animal; Blood Pressure; Cardiomegaly; English Abstract; Heart; Hypertension; Male; Myocardial Contraction; Myocardium; Rabbits; Time Factors
Date of creation
19.10.2018
Date of change
19.10.2018
Short link
https://repository.rudn.ru/en/records/article/record/1474/