РОЛЬ ПЕРОКСИРЕДОКСИНА В ФОРМИРОВАНИИ ЛЕКАРСТВЕННОЙ УСТОЙЧИВОСТИ ОПУХОЛЕВЫХ КЛЕТОК

ROLE OF PEROXIREDOXIN IN THE DEVELOPMENT OF DRUG RESISTANCE OF CANCER CELLS

Redox-dependent processes to a significant extent determine functional actions of many proteins and as a consequence redox-dependent regulation of important cellular functions such as proliferation, differentiation, apoptosis. In this paper we report the results of study of the role of peroxiredoxin isoforms in redox-dependent mechanism of development of drug resistance of cancer cells.

Authors
Калинина Е.В. (Kalinina E.V.) 1 , Березов Т.Т. (Berozov T.T.) 1 , Чернов Н.Н. (Chernov N.N.) 1 , Новичкова М.Д. (Novichkova M.D.) 1 , Нурмурадов Н.К. (Nurmuradov N.K.) 1 , Штиль А.А. (Shtil A.A.) 2 , Глазунова В.А. (Glasunova V.A.) 2
Journal
Журнал научных статей Здоровье и образование в XXI веке
Publisher
Некоммерческое партнерство Сообщество молодых врачей и организаторов здравоохранения
Issue number
4
Language
Russian
Pages
415-416
State
Published
Volume
14
Year
2012
Organizations
  • 1 RPFU
  • 2 Blokhin Russian Cancer Research Center
Keywords
peroxiredoxin; drug resistance of cancer cells; doxorubicin; cisplatin
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