Mass-spectral investigation of pyrrolo[3,2-c]piperidines

The dissociative ionization of derivatives of pyrrolo[3,2-c]piperidines and their deutero analogs was studied. The successive elimination of the substituents in the piperidine ring, which leads to its aromatization, and cleavage of this ring via a retrodiene fragmentation mechanism are the principal pathways of fragmentation of these substances. The principles found make it possible to determine the position and character of the substituents in the piperidine ring of derivatives of pyrrolo[3,2-c]piperidines. © 1988 Plenum Publishing Corporation.