A Computational Model of Some Key Socially Significant Processes

This work deals with the tasks and relevance of mathematical computer modeling of biological systems and, in particular, simulation modeling. A discrete computer mathematical model presented is suitable for the ischemic stroke pathogenesis outlook engaged with an appropriate computer program described. For the first time, the results of stroke modeling performed by stochastic Monte Carlo method with the brain neurovascular units as elementary structures of the system have been proposed. Conclusions are drawn taking into account an applied pharmacological potential of the model for the current preclinical trails requirements.

Авторы
Fursov V.V. 1, 2, 3 , Ananyev A.V.1 , Ananishnev V.M.4 , Tkachenko A.V.4 , Osmolovskaya S.M.4 , Berestova L.I.5 , Frolova T.N.6
Номер выпуска
S7
Язык
Английский
Страницы
010623
Статус
Опубликовано
Том
16
Год
2022
Организации
  • 1 Mendeleev University of Chemical Technology of Russia
  • 2 The Russian National Research Medical University named after N.I. Pirogov
  • 3 Peoples' Friendship University of Russia
  • 4 Moscow City University
  • 5 The Russian Presidential Academy Of National Economy And Public Administration
  • 6 Federal State Public Educational Establishment of Higher Professional Training Moscow University of the Ministry of the Interior of the Russian Federation named after V.Y. Kikot
Ключевые слова
mathematical computer modeling; simulation modeling; stroke; Monte Carlo method; discrete model; neurovascular unit
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