PROBLEMS OF ANTICOAGULATION THERAPY IN PATIENTS WITH CHRONIC HEART FAILURE AND ATRIAL FIBRILLATION: ROLE OF RIVAROXABAN

Heart failure and atrial fibrillation are the two new epidemics of cardiovascular disease. Their frequent coincidence increases mortality rates mainly because of increased risk of thromboembolic events. The review focuses on epidemiology, mechanisms, prognosis in patients with heart failure and atrial fibrillation, approaches to the administration of direct oral anticoagulants and role of rivaroxaban.