Uric acid - the key component of "cardio-reno-metabolic continuum"

The recently emerged concept of cardio-reno-metabolic continuum supports common pathogenesis, development and progression risk factors (RF) for renal dysfunction and cardiovascular disease (CVD), as well as the importance of renal dysfunction, from subclinical disturbances to terminal renal failure, for CVD outcomes. The review summarizes the data on uric acid as a marker of renal dysfunction and CVD RE Original results, obtained by the authors, are also presented.