The article presents an overview of the most significant results in Russian academic research in philosophy of the Arabic Middle East in the second half of the XX century—the beginning of XXI century. The author consistently examines the contribution of various schools and their main representatives to the field of Arabic studies, in particular, the academic research works dedicated to the Middle East philosophy and history written by the scientists from the Institute of Philosophy of the Russian Academy of Sciences, the Institute of Oriental Studies of the Russian Academy of Sciences, Lomonosov Moscow State University, Saint Petersburg State University and RUDN University. The article attempts to show the conceptual findings and results of this academic research on Arabic Islamic philosophy of the Middle Ages considering the problems of understanding and interpreting Arab and Muslim culture, which was held by a number of leading experts during the second half of the XX century, up to the early XXI century. It is equally important to understand the role and place of the historical and philosophical Arabic studies in the dialogue between different philosophical cultures — in the context of striving for responses to the challenges of the modern time. The author of the article proves the idea that overcoming false cultural, philosophical and ideological stereotypes in the unprecedented global interaction of East and West in the late XX and early XXI centuries will significantly expand academic mobility and internationalization in the fields of education and science, open new perspectives for international cooperation in various fields and promote mutual enrichment of cultures. © 2021, RUDN UNiversity. All rights reserved.