Application of polyhexanide as a new highly effective antiseptic composition

Currently, antiseptics are used at all stages of surgical treatment. Currently, the search con-tinues for antiseptics that have effective properties in suppressing pathological microflora and as safe as possible in relation to tissues. One of the promising antiseptic solutions is a solution based on polyhexanide. The aim of this work was to study the available reports on the effectiveness of the polyhexanide solution, its safety, and experience of use. To assess the effectiveness of using a polyhexonide solution as an antiseptic, a search was made for publications in the scientific databases “PubMed” and “Google Scholar”. A total of 2026 scientific articles were found during the search. When studying the content of the texts, 31 articles were accepted for consideration, corresponding to the given criteria. Polyhexanide solution is widely used in surgical practice. In wound healing, antiseptic treatment is one of the key steps. The suppression of the reproduction of pathological microflora and the effect on the biofilm is extremely important. When analyzing the publications, different results were noted using the polyhexanide solution. Studies of the effectiveness of the polyhexanide solution are currently being actively pursued. Due to its significant efficacy, safety, and ease of use, polyhexamethylene biguanide is promising for use in surgical practice. © 2022, Yerevan State Medical University. All rights reserved.