Spectral Decomposition of Mappings of Molecular Genetic Information in the System Basis of Single Nucleotide Functions

This paper presents and visualizes examples of large amounts of genetic information using a new class of cognitive computer graphics algorithms. These algorithms are related to the semiotics of perception and allow the interpretation of those properties of nucleotide sequences that are difficult to perceive by simple reading or by standard means of statistical analysis. This article summarizes previously presented algorithms for visualizing long nucleic acids based on the primary Hadamard–Walsh function system. The described methods allow us to produce one-dimensional mappings of nucleic acids by levels corresponding to their scale-integral physicochemical parameters and construct a spectral decomposition of the nucleotide composition. An example of the spectral decomposition of parametric representations of molecular genetic structures is given. In addition, a multiscale composition of genetic functional mappings visualizing the structural features of nucleic acids is discussed. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.

Авторы
Stepanyan I. 1, 2 , Lednev M.2
Журнал
Издательство
MDPI AG
Номер выпуска
5
Язык
Английский
Статус
Опубликовано
Номер
844
Том
14
Год
2022
Организации
  • 1 Peoples’ Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Street, Moscow, 117198, Russian Federation
  • 2 Mechanical Engineering Research Institute of the Russian Academy of Sciences (IMASH RAN), M. Kharitonyevskiy Pereulok, Moscow, 101990, Russian Federation
Ключевые слова
big data; chromosomes; decomposition; DNA; geometry; nucleotides; spectral analysis; visualization
Дата создания
06.07.2022
Дата изменения
06.07.2022
Постоянная ссылка
https://repository.rudn.ru/ru/records/article/record/83645/
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