Anatomical Considerations and Emerging Strategies for Reducing New Onset Conduction Disturbances in Percutaneous Structural Heart Disease Interventions

Transcatheter procedures offer an alternative to cardiac surgery in select patients with structural heart disease (SHD). Unfortunately, inadvertent disruption of electrical pathways and subsequent development of new onset conduction disturbances can occur in up to 5–70% of percutaneous interventions, result in pacemaker implantation, and confer a worse prognosis. The physical proximity between the conduction system (atrioventricular node, bundle of His, and bundle branches) and the site of percutaneous repair is increasingly recognized as a key factor influencing new onset conduction disturbance development in procedures located near the conduction system. This review covers the incidence, clinical significance, and mechanisms of new onset conduction disturbances and discusses current and emerging strategies to address this complication in these populations. Abbreviations: SHD: structural heart disease; AVN: atrioventricular node; AVB: atrioventricular block; LBBB: left bundle branch block; PPM: permanent pacemaker.

Авторы
Albaghdadi M.S.1, 2 , Kadlec A.O.3 , Sievert H. 4, 5 , Mahapatra S.6 , Romanov A.7 , Siddiqui U.8 , Kronzon I.9 , Young M.N.10 , Tzikas A.11 , Leon M.B.12, 13 , Ho S.Y.14 , Kuck K.H. 15
Журнал
Издательство
Bellwether Publishing, Ltd.
Язык
Английский
Статус
Опубликовано
Год
2021
Организации
  • 1 Division of Cardiology|Massachusetts General Hospital
  • 2 Division of Cardiology|Department of Medicine|University of Toronto
  • 3 Cardiovascular Center|Medical College of Wisconsin
  • 4 Department of Cardiology
  • 5 Department of Cardiology|Anglia Ruskin University
  • 6 Division of Cardiology|University of Minnesota
  • 7 E. Meshalkin National Medical Research Center of the Ministry of Health of the Russian Federation
  • 8 Division of Cardiology|Advent Health Celebration
  • 9 [8] Division of Cardiology|Lenox Hill Heart and Vascular Institute of New York
  • 10 Cardiology Division|Dartmouth-Hitchcock Medical Center|Geisel School of Medicine
  • 11 AHEPA University Hospital & European Interbalkan Medical Center
  • 12 Division of Cardiology|Columbia University Medical Center|New York-Presbyterian Hospital
  • 13 The Cardiovascular Research Foundation
  • 14 Cardiac Morphology|Royal Brompton Harefield NHS Trust|Imperial College London
  • 15 Department of Cardiology|Asklepios Klinik St. Georg
Ключевые слова
New onset conduction disturbances; Percutaneous interventions; structural heart disease
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