The biochemical intensity markers of free radical processes in blood and oral liquid of patients with atopic dermatitis are presented in this article. To appraise the oxidative metabolism condition the biophysical parameters such as the flash maximum and. H2O2 area of induced chemiluminescence and the concentration of biomolecular oxidative modification's products which can react on thiobarbituric acid were studied.. In the course of the research it was found, that a significant increase of free radical processes was marked in the blood, while in the oral cavity it was less expressed changes. These changes allow us to speak about the prospects of the use of oral liquid as the material for the development of non-invasive methods for diagnosis of metabolic rates of the body.