The decrease in the content of heavy isotopes of hydrogen (D) and oxygen (17O, 18O) in water is accompanied by a change in metabolic processes in plant and animal organisms, which is explained by the isotopic kinetic effect. This phenomenon underlies the technology of accumulation of microelements in medicinal and non-medicinal plants used for soft correction of hypoelementoses. The new technology includes isotope management of plant development; new laser methods for end-to-end quality control of aqueous solutions for irrigation and hydroponics of plants; a set of methods for end-to-end control of plant raw material enrichment in a microelement; online control of biotoxicity of plant raw materials and medicines made from them. Thus, in our work, the possibility of the development of metal-modified plants with zinc content of 1.4 mg/g dry basis is shown. © 2020 EManuscript Technologies. All rights reserved.