Objective: Anatomizing the mental spine area, nutrient foramen system, and mandibular canal to discover anatomical and radiological features of the mandibular mental region. Materials and Methods:Research involved an anatomical study, namely manufacture of gross specimens stained by in-house methods to detect the vascular-nervous tract. It involved craniometric measurements of 200 corpses aged 50-70 without maxillofacial pathology. Using a Gigli saw helped obtain and examine 200 mandibular fragments. The resulting defect was replaced, using an alginate fragment and mimicking denture teeth. The tract was anatomized under the binocular loupe MBS-2, using microsurgical instruments. Bone specimens with the separated vascular-nervous tract were examined by macro- and micro-preparation methods. Results: Comparison of anatomical and radiological findings revealed correlation between the skull type and the mental foramen shape. Macroanatomical and radiological findings showed 3 types of the mental spine canal. Conclusion: The results of the work conducted provide a fair presentation of the peculiar structure of the mental cavity and the intra- and endoosseous branches of the mental nerve, and the canal of its end correlates with the mental spine canal.