ASSOCIATION OF DNA FRAGMENTATION OF SPERMATOZOA AND THE SUCCESS OF ASSISTED REPRODUCTIVE TECHNOLOGY PROGRAMS

The number of men with impaired sperm genetic material is steadily increasing, which is reflected in the increase in the number of assisted reproductive technology (ART) programs and their outcomes. This article presents an analysis of ART program success, depending on the proportion of DNA-sperm fragmentation. As a result, in couples with normal sperm counts (n=43), the frequency of spontaneous abortions was twice lower compared to couples (n=39), where the level of DNA fragmentation was increased (p<0.05) CONCLUSIONS. The miscarriage in a spouse in the early stages (up to 12 weeks) is more common in couples with damaged sperm DNA.