ANTIMICROBIAL THERAPY OF ACUTE UNCOMPLICATED CYSTITIS WITH NIFURATEL

The article evaluates the effectiveness of the antimicrobial therapy of acute cystitis with nifuratel in 35 women (400 mg - 3 times a day orally). The control group of the study included 31 women who used nitrofurantoin (100 mg - 2 times a day) to treat acute uncomplicated cystitis. We examined the women on the third and seventh day of the intake. Three days after the use of nifuratel (1200 mg/day), the majority of patients (94.2%) subjectively noted the disappearance of urgency, leukocyturia disappeared in 82.8%. 22.8% of women remained uncomfortable when urinating, and we decided to extend the course of antimicrobial therapy with nifuratel up to 7 days. Three days after intake of nitrofurantoin (200 mg/day), 83.8% of women subjectively noted the disappearance of urgency, leukocyturia was stopped in 77.4%. Thus, in 12 (38.7%) cases the decision was taken to extend the course of antimicrobial therapy with nitrofurantoin up to 7 days. In the first group of patients side reactions occurred only in 3 (8.5%) cases, in the second - in 13 (41.9%). Efficiency, favorable safety profile and absence of allergic reactions make nifuratel reliable in the treatment of acute uncomplicated cystitis.