On optimal therapy protocols in the mathematical model of prostate cancer progression

A mathematical model for the treatment of prostate cancer regarding androgen ablation is considered. The effect of the therapy on healthy cells is taken into account and modelled as a second order state constraint. A mathematical overview about possible therapy strategies is presented. © 2020 ASSA.

Авторы
Litzinger M.-C.1 , Todorov Y.1 , Föller-Nord M.1 , Chaudhary M.K. 2 , Bratus A.S.3, 4
Журнал
Достижения в области системных наук и приложений
Издательство
International Institute for General Systems Studies
Номер выпуска
4
Язык
Английский
Страницы
83-104
Статус
Опубликовано
Ссылка
Внешняя ссылка
DOI
10.25728/ASSA.2020.20.4.998
Том
20
Год
2020
Организации
  • 1 University of Applied Sciences, Paul-Wittsack-Str. 10, Mannheim, 68163, Germany
  • 2 Nikolsky Mathematical Institute, Rudn University, Miklukho-Maklaya str.6, Moscow, 117198, Russian Federation
  • 3 Russian University of Transport, Obraztsova 15, Moscow, 127994, Russian Federation
  • 4 Moscow Center of Fundamental and Applied Mathematics, MSU, GSP-1, Leninskie Gory, Moscow, 119991, Russian Federation
Ключевые слова
Androgen ablation; Optimal control; Prostate cancer; State constraint; Therapy strategies
Цитировать
ГОСТ MLA RIS BibTex
Поделиться

Другие записи