Polymers for the enhancement of solubility of pharmaceutical substances in solid drug formulations

This review presents the survey of basic properties of polymers. As potential solubilizers for pharmaceutical formulations with low solubility in water, diverse polymeric excipients containing various functional groups are considered. © 2018, Springer Science+Business Media, LLC, part of Springer Nature.

Авторы
Yudina D.V.1 , Blynskaja E.V.1 , Alekseev K.V. 2 , Marakhova A.I. 3
Журнал
Russian Chemical Bulletin
Номер выпуска
5
Язык
Английский
Страницы
787-791
Статус
Опубликовано
Ссылка
Внешняя ссылка
DOI
10.1007/S11172-018-2138-Z
Том
67
Год
2018
Организации
  • 1 Zakusov Research Institute of Pharmacology, 8 ul. Baltiiskaya, Moscow, 125315, Russian Federation
  • 2 Moscow Medical University “Reaviz”, 2 Build. 2 ul. Krasnobogatyrskaya, Moscow, 107564, Russian Federation
  • 3 The RUDN Universtiy, 64 ul. Miklukho-Maklaya, Moscow, 117198, Russian Federation
Ключевые слова
bioavailability; excipients; pharmaceutical substance; polymers; poor solubility; solid dispersion; solubilization
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