A novel method for the extraction of the main compounds from the essential oil of clove buds

The purpose of this work was to test a hypothesis about the possibility of extraction of the main clove buds essential oil substances from with two different types of perfluoro organic solvents, Novec 1230 and Novec 7100. Using simple maceration method, it was found out that the maximum yield of eugenol was observed into n-hexane: 81 ± 4%. The yield of eugenol into perfluoro organic solvent Novec 7100 was 73 ± 4% and into the perfluoro organic solvent Novec 1230 was 6.9 ± 0.4%. Using the extraction circulation method, it was found that the yield of eugenol into perfluoro organic solvent Novec 7100 in 2 h of circulation was 85 ± 4%. Under the same conditions, the yield of eugenol into the perfluoro organic solvent Novec 1230 was 54 ± 3% during 4 h of its circulation. © 2020, Romanian Society for Pharmaceutical Sciences. All rights reserved.