This review focuses on current data sources on medicinal plants possessing expectorant effects. The component characterization of biologically active compounds determining the specified pharmacological effect of herbal medicines was also described and analyzed. The nomenclature of expectorant drugs presented on the Russian pharmaceutical market was studied and trends have been identified. It is known that herbal preparations, as a rule, are multicomponent. Combined expectorant drugs that simultaneously affect various mechanisms of inflammation and cough are becoming increasingly popular in medical practice. It seems relevant to assess the proportion of the most commonly used components (as well as biologically active substances) that are currently used for the production of expectorant drugs. Expectorant herbal preparations may contain such groups of biologically active substances as polysaccharides, saponins, essential oils, alkaloids. Medicinal plant material with an expectorant effect is used to obtain liquid dosage forms: syrups, tinctures, infusions, decoctions, elixirs, drops, and oral solutions, as well as solid - tablets, capsules, granules, troches, powders. These drugs occupy their important niche in the pharmaceutical market of the Russian Federation. © 2020 EManuscript Technologies. All rights reserved.