Effect of the carotid body excision on the development of corazol-induced seizures

Bilateral glomectomy in albino rats produced protective effect against the development of corazol seizures, which was manifested in prolonged latency of seizures and a 2-fold shortening of their total duration. Acute hypoxia led to shortening of the latency both in glomectomized and in sham-operated rats and significantly decreased the number of seizures in glomectomized rats, although a similar decrease in sham-operated rats was insignificant. Possible participation of sinocarotid reflexogenic zones in hypoxic protection against experimental seizures is discussed. © 1999 Kluwer Academic/Plenum Publishers.