The paper deals with the problem of existence and construction of limiting characteristics for timeinhomogeneous birth and death processes which is important for queueing applications. For this purpose we calculate the limiting characteristics for the process via the construction of two-sided uniform in time truncation bounds.We consider theMt|Mt|S queueing model and obtain uniform approximation bounds of two-sided truncations. A numerical example is considered. Our approach to truncations of the state space can be used in modeling information flows related to high-performance computing. © ECMS Zita Zoltay Paprika, Péter Horák, Kata Váradi,Péter Tamás Zwierczyk, Ágnes Vidovics-Dancs, János Péter Rádics (Editors).