Comment on "an unexpected formation of the novel 7-oxa-2-azabicyclo[2.2.1]hept-5-ene skeleton during the reaction of furfurylamine with maleimides and their bioprospection using a zebrafish embryo model" by C. E. Puerto Galvis and V. V. Kouznetsov,: Org. Biomol. Chem., 2013, 11, 407

It has been proved that the reaction between furfuryl amines and N-R-maleimides leads to the formation of aza-Michael addition products-3-(furylmethylamino)-N-R-pyrrolidine-2,5-diones, instead of 7-oxa-2-azabicyclo[2.2.1]hept-5-enes, as this journal reported previously. © The Royal Society of Chemistry 2017.

Авторы
Zubkov F.I. 1 , Kvyatkovskaya E.A. 1 , Nikitina E.V. 1 , Amoyaw P.N.-A. 1 , Kouznetsov V.V. 2 , Lazarenko V.A. 3 , Khrustalev V.N. 4
Журнал
Organic and Biomolecular Chemistry
Издательство
Royal Society of Chemistry
Номер выпуска
30
Язык
Английский
Страницы
6447-6450
Статус
Опубликовано
Ссылка
Внешняя ссылка
DOI
10.1039/C7OB01207A
Том
15
Год
2017
Организации
  • 1 Department of Organic Chemistry, Peoples Friendship University of Russia, RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russian Federation
  • 2 Laboratorio de Química Orgánica y Biomolecular, CMN, Universidad Industrial de Santander, Parque Tecnológico, Guatiguara Km 2 vía refugio, Piedecuesta, A.A. 681011, Colombia
  • 3 NRC Kurchatov Institute, 1 Acad. Kurchatov Sq., Moscow, 123182, Russian Federation
  • 4 Department of Inorganic Chemistry, Peoples Friendship University of Russia, RUDN University, 6 Miklukho-Maklaya St., Moscow, 117198, Russian Federation
Ключевые слова
Addition reactions; Aza-Michael addition products; Bioprospection; Furfuryl amines; Maleimides; Pyrrolidines; Zebrafish embryos; Chemical reactions
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